Entrapment of vitamins with an elastomeric silicone polyether

Drug – bio-affecting and body treating compositions – Designated organic nonactive ingredient containing other... – Aftertreated solid synthetic organic polymer

Reexamination Certificate

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Reexamination Certificate

active

06207717

ABSTRACT:

CROSS-REFERENCE TO RELATED APPLICATIONS
Not applicable.
STATEMENT REGARDING FEDERALLY SPONSORED RESEARCH OR DEVELOPMENT
Not applicable.
REFERENCE TO A MICROFICHE APPENDIX
Not applicable.
FIELD OF THE INVENTION
This invention is directed to entrapping vitamins with an elastomeric silicone polyether. In particular, oil-soluble vitamins such as vitamin A and vitamin E are delivered to substrates such as hair, skin, or the underarm, by entrapping the vitamin in the oil phase in the elastomeric silicone polyether.
BACKGROUND OF THE INVENTION
Natural and synthetic vitamins have been extensively used in various types of skin and cosmetic compositions. Although different methods have been proposed for entrapping and formulating vitamins into skin and cosmetic compositions, the known methods typically require the use of an anhydrous composition or a water-in-organic oil emulsion, both of which are greasy, and therefore cosmetically less appealing. In other instances, the known methods employ a very complicated stabilization system, when one desires to form a less greasy oil-in-water emulsion.
The present invention, in contrast, is based upon an elastomeric silicone polyether which can be used to entrap and formulate vitamins into skin and cosmetic compositions, and which can be used to form less greasy water-in-oil emulsions without requiring additional surfactants. This can be of considerable value in the personal care arena where skin sensitivity due to the presence of certain surfactants can be an issue. The method of making the vitamin entrapped compositions according to this invention is simple, and it does not require the use of high shear or heating. In addition, the elastomeric silicone polyether is capable of providing aesthetic benefits.
While U.S. Pat. 5,811,487 (Sep. 22, 1998), assigned to the same assignee as the present invention, broadly suggests that vitamins can be delivered with an elastomeric silicone polyether, the elastomeric silicone polyether in the '487 patent may contain anywhere from zero to 100 ethylene oxide (EO) units in its molecule. According to this present invention, however, it has been unexpectedly discovered that effective vitamin delivery can only be accomplished by using an elastomeric silicone polyether containing 4-30 (EO) units in its molecule. Moreover, in the case of vitamin A, there is required 7-30, rather than 4-30 (EO) units. This improved performance in a range within the range of the '487 patent is unexpected.
Furthermore, and according to this invention, it has also been unexpectedly discovered that effective vitamin delivery can only be accomplished by using an elastomeric silicone polyether prepared according to a method in which the equivalent ratio of the ≡SiH in the ≡SiH containing polysiloxane with polyether groups and the unsaturated hydrocarbon is 2:1 to 1:2. In contrast, the '487 patent employs an elastomeric silicone polyether prepared according to a method in which the equivalent ratio of the ≡SiH in the ≡SiH containing polysiloxane with polyether groups and the unsaturated hydrocarbon is 20:1 to 1:20. Again, improved performance in a range within the range of the '487 patent is unexpected.
In addition, nothing in the '487 patent suggests that oil-soluble vitamins such as vitamin A and vitamin E can be entrapped in the oil phase of elastomeric silicone polyethers.
BRIEF SUMMARY OF THE INVENTION
This invention relates to a method of making a vitamin enhanced silicone elastomer by entrapping a vitamin in an elastomeric silicone polyether. The vitamin is entrapped in the elastomeric silicone polyether by mixing the vitamin with the elastomeric silicone polyether. The elastomeric silicone polyether is a composition prepared by reacting (A) an ≡Si—H containing polysiloxane and (B) a mono-alkenyl polyether in the presence of a platinum catalyst, until (C) an ≡Si—H containing polysiloxane with polyether groups is formed. The ≡Si—H containing polysiloxane with polyether groups (C) is then reacted with (D) an unsaturated hydrocarbon such as an alpha, omega-diene, an alpha, omega-diyne, or an alpha, omega-ene-yne, in the presence of (E) an oil and a platinum catalyst, until a silicone elastomer is formed by crosslinking and addition of ≡SiH across double or triple bonds in the unsaturated hydrocarbon.
If desired, all of the reactants (i.e., the ≡SiH containing siloxane(s), the mono-alkenyl polyether, the unsaturated hydrocarbon, the oil, and the platinum catalyst), can be combined and reacted in one pot, as described in copending U.S. patent application Ser. No. 08/866,993, filed Jun. 2, 1997, and assigned to the same assignee as the present application.
The invention also relates to a method of entrapping and delivering oil-soluble vitamins to a substrate using the elastomeric silicone polyether. Compositions according to the invention generally contain 0.01 to 50 percent by weight of a vitamin or a mixture of vitamins, 0.01 to 50 percent by weight of the elastomeric silicone polyether, with the balance of the composition being an oil.
Water-in-oil emulsions can be formed by using the composition as an oil phase. Thus, by adding water to the oil phase and shearing, water-in-oil emulsions can easily be manufactured. The entrapped vitamins remain in the oil phase after formation of the emulsion.
These elastomeric silicone polyether entrapped vitamins, as well as the water-in-oil silicone emulsions prepared using the elastomeric silicone polyether entrapped vitamins, are of value in treating substrates such as hair, skin, and the underarm areas of the human body.
These and other features of the invention will become apparent from a consideration of the detailed description.


REFERENCES:
patent: 3920805 (1975-11-01), Roseman
patent: 4230686 (1980-10-01), Schopflin et al.
patent: 5364633 (1994-11-01), Hill
patent: 5654362 (1997-08-01), Schulz
patent: 5665804 (1997-09-01), Hill
patent: 5811487 (1998-09-01), Schulz et al.
patent: 440398 (1991-08-01), None
patent: 631772 (1995-01-01), None
patent: 832643 (1998-04-01), None
patent: 9300085 (1993-01-01), None

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