Enterosoluble capsules

Details Enterosoluble capsules Enterosoluble capsules

1980-04-15

1982-12-21

Lieberman, Allan

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

536 66, 424 35, C08B 316, C08B 1300

Patent

active

043650600

ABSTRACT:
The invention provides a novel enterosoluble capsule for containing a medicament, which is shaped with a hitherto not used novel cellulose derivative. The cellulose derivative is a mixed ester of an alkyl-, hydroxyalkyl- or hydroxyalkyl alkylcellulose esterified with succinyl anhydride and an aliphatic monocarboxylic acid anhydride. The enterosoluble capsules have excellent enterosolubility behavior as well as sufficient pliability even without the addition of a plasticizer which is almost indispensable in the prior art materials. The cellulose derivative can be shaped into capsules not only by the conventional dipping method but also by the plastic deformation at an elevated temperature under pressure such as compression molding, vacuum forming, matchedmold forming and the like.

REFERENCES:
patent: 2794799 (1957-06-01), Hiatt et al.
patent: 2856399 (1958-10-01), Mench et al.
patent: 3493407 (1970-02-01), Greminger
patent: 4017647 (1977-02-01), Ohno
patent: 4138013 (1979-02-01), Okajima
patent: 4226981 (1980-10-01), Onda

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