Enterococcus antigens and vaccines

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...

Reexamination Certificate

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C424S831000, C424S134100, C435S007320

Reexamination Certificate

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10876758

ABSTRACT:
A majority ofE. faecalisandE. faeciumclinical isolates fall into two groups and three groups, respectively. Distinct antigens are associate with each of the five groups. TheEnterococcusantigens are readily obtained from strains ofE. faecalisandE. faecium, and can elicit production of protective antibodies. Accordingly, the antigens are useful for vaccines which protect against infection by clinically significant (pathogenic)Enterococcusisolates. The antigens and antibodies generated to the antigens are also useful in diagnostic assays.

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