Drug – bio-affecting and body treating compositions – Plant material or plant extract of undetermined constitution...
Reexamination Certificate
2008-01-29
2008-01-29
Marx, Irene (Department: 1651)
Drug, bio-affecting and body treating compositions
Plant material or plant extract of undetermined constitution...
C514S183000, C514S732000, C514S867000
Reexamination Certificate
active
07323195
ABSTRACT:
Pharmaceutical compositions containing a proanthocyanidin polymer composition which are useful for the treatment and prevention of secretory diarrhea are provided. The invention specifically relates to pharmaceutical formulations of a proanthocyanidin polymer composition which has been isolated from aCrotonspp. or aCalophyllumspp. In particular, the invention relates to a formulation of a proanthocyanidin polymer composition which protects the composition from the effects of stomach acid after oral administration, particularly to those formulations which are enteric coated. The invention also relates to methods of producing a directly compressible proanthocyanidin polymer composition, as well as compositions containing the directly compressible proanthocyanidin polymer composition.
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Balwani Gul P.
Chan Jody Wai-Han
Khandwala Atul S.
Rozhon Edward James
Sabouni Akram
King & Spalding LLP
Marx Irene
Napo Pharmaceuticals, Inc.
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