Enteric film and preparatoin thereof

Details Enteric film and preparatoin thereof Enteric film and preparatoin thereof

1990-03-23

1993-03-16

Kight, III, John

Synthetic resins or natural rubbers -- part of the class 520 ser

Synthetic resins

Processes of preparing a desired or intentional composition...

524 43, 524 77, 1061631, 106170, 106178, 106180, 106188, 106189, 1061972, 106198, 427 3, 427214, 427220, 427221, 424463, C08L 126, C08L 108, B05D 700

Patent

active

051944642

ABSTRACT:
An enteric film is produced by spraying on a material a mixed solution of (a) hydroxypropylmethylcellulose phthalate exhibiting a viscosity of about 136 to 204 centistokes as 10% methanol/dichloromethane (1:1 by weight) solution at 20.degree. C., (b) polyethylene glycol presenting solid state at ambient temperature and (c) shellac, wherein respective ratios of (b) and (c) to (a) are 0.1 to 20 weight percent and 5 to 40 weight percent; and then drying the solution.
The enteric film excels in film strength and acid resistance, and can be employed in pharmaceutical preparations.

REFERENCES:
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patent: 3149039 (1964-09-01), Jefferies
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patent: 3297535 (1967-01-01), Butler et al.
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patent: 3539380 (1970-11-01), Johnson
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patent: 4670287 (1987-06-01), Tsuji
patent: 4816259 (1989-03-01), Matthews et al.
Japanese Pharmacopeia, 11th Rev. Ed. "Hydroxy propylmethylcellulose phthalate 200731," Chemical Abstract 111:120929s Enteric-Coating Soft Gelatin Capsules Containing Hydroxypropyl Methyl Cellulose & Polyethylene Glycol.
Catalog of HP-MCP, Shin-Etsu Chemical Company, Ltd., Tokyo, Japan (1985).

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