Enteric disease vaccine

Details Enteric disease vaccine Enteric disease vaccine

1975-03-19

1976-08-17

Rose, Shep K.

Drug, bio-affecting and body treating compositions

Lymphokine

424 92, 424 93, 426583, 426585, A61K 3940, A23C 900, A23C 2100

Patent

active

039755177

ABSTRACT:
Preparation of and live bacterial vaccine from selected strains of Escherichia coli. The bacterial cells are treated with dilute formalin solutions (about 0.02 to about 0.08% v/v formalin) for a period to modify the bacteria without inactivation thereof. One preferred strain is EW1 serogroup of 0157. The vaccine has been found particularly effective in preventing the occurrence of enteric colibacillosis in newborn animals. A preferred technique is to vaccinate cows, recover the milk, and continually feed it as a milk replacer to the newborn during the susceptible period.

REFERENCES:
patent: 2110208 (1938-03-01), Eggert
patent: 3127318 (1964-03-01), Eversole et al.
patent: 3128230 (1964-04-01), Heinbach
patent: 3376198 (1968-04-01), Peterson et al.
patent: 3907987 (1975-09-01), Wilson
Wilson et al., Vet. Bul. 41(12), No. 6106, Dec. 1971.
Wilson et al., Vet. Bul. 42(3), No. 1159, Mar. 1972.
Svendson et al., Vet. Bul. 42)3), No. 1154, Mar. 1972.
Wilson et al., Vet. Bul. 42(12), No. 7100, Dec. 1972.
Wilson, Vet. Bul. 43(4), No. 1451, Apr. 1973.

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