Enteric capsules

Details Enteric capsules Enteric capsules

1977-06-13

1979-02-06

Hayes, Lorenzo B.

Special receptacle or package

For ampule, capsule, pellet, or granule

106128, 106137, 106189, 106193D, 106197R, 206529, 260 8, 424 32, 424 35, 424 37, 427 3, A61K 958

Patent

active

041380134

ABSTRACT:
Pharmaceutical capsules with telescopically engaged body and cap portions, also known as hard shell capsules, having enteric properties. The capsule body and cap portions are formed by dip-molding using a homogeneous film-forming mixture comprising (1) hydroxypropyl methylcellulose and an ammonium salt of cellulose acetate phthalate polymer, or (2) gelatin and an ammonium salt of a copolymer of methacrylic acid and methacrylic acid alkyl ester; optionally with the inclusion of plasticizer and/or coloring agent. The capsules are soluble in or disintegrated by the alkaline intestinal secretions but are substantially insoluble or resistant to solution in the acid secretions of the stomach.

REFERENCES:
patent: 2718667 (1955-09-01), Malm et al.
patent: 3826666 (1974-07-01), Hirai et al.
patent: 3859228 (1975-10-01), Morishita et al.
patent: 4001390 (1977-01-01), Ohno et al.

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