Entamoeba histolytical immunogenic protein and cDNA clone

Details Entamoeba histolytical immunogenic protein and cDNA clone Entamoeba histolytical immunogenic protein and cDNA clone

1990-04-30

1992-07-14

Lacey, David L.

Chemistry: natural resins or derivatives; peptides or proteins;

Proteins, i.e., more than 100 amino acid residues

536 27, 435 693, 4353201, 424 88, 530822, 930210, C07K 1300, C12N 1530

Patent

active

051304171

ABSTRACT:
An Entamoeba histolytica specific cDNA clone which encodes an antigenic surface membrane protein possessing multiple tandem repeats and expression in E. coli is disclosed.

REFERENCES:
ATCC Catalog of Protists, 17th Edition, 1991 pp. 20-21.
"Servo Diagnosis of Invasive Asmebiosis Using a Recombinant Entamoeba Histolytica Protein" Starley et al., JAMA, vol. 266(14) pp. 1984-1986 Oct. 9, 1991.
Tannich et al., Proc. Natl. Acad. Sci. USA 86, 5118 (1989).
Hardy & Strauss, Chem. Absts. 108:128277 (1988).
Kemp et al., Ann. Rev. Microbiol. 41, 181 (1987).
Ozaki et al., Cell 34, 815 (1983).
Galinski et al., Cell 48, 311 (1987).
Li et al., Chem. Absts. 110:55218 (1989).
Tachibana et al., "Identification of a Pathogenic Isolate-Specific 30,000-M.sub.r Antigen ", Infection and Immunity, vol. 58(4) 955-960 Apr. 1990.

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