Enriched plasma derivative for enhancement of wound closure and

Details Enriched plasma derivative for enhancement of wound closure and Enriched plasma derivative for enhancement of wound closure and

1982-06-07

1984-01-24

Rosen, Sam

Drug, bio-affecting and body treating compositions

Effervescent or pressurized fluid containing

Organic pressurized fluid

424 45, 424101, 424177, A61K 914, A61K 3514, A61K 3700

Patent

active

044276516

ABSTRACT:
A sprayable preparation for accelerated hemostasis and optimized biochemical control of wound closure contains a powdery mixture of 15 to 60% by weight of thrombin, 5 to 80% by weight of a desiccating and stabilizing agent, viz., albumin, globulin and/or fibrinogen, and 1 to 10% by weight of a fibrinolysis inhibitor. The powdery mixture is suspended in a low-boiling, anhydrous solvent, which is used as a propellant. For effective wound closure and coverage, a spray jet of this suspension is directed onto the wound under evaporation of the solvent so that substantially only the dry, solid powdery mixture reaches the wound. This method of application by spraying is also disclosed.

REFERENCES:
patent: 4298598 (1981-11-01), Schwarz et al.
patent: 4362567 (1982-12-01), Schwarz et al.
Schwarz et al.--Chem. Abst., vol. 94 (1981), p. 36318q.
Schwarz et al.--Chem. Abst., vol. 94, (1981), p. 36384h.
McKendrick et al.--Chem. Abst., vol. 76 (1972), p. 17809n.

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