Drug – bio-affecting and body treating compositions – Effervescent or pressurized fluid containing – Organic pressurized fluid
Patent
1982-06-07
1984-01-24
Rosen, Sam
Drug, bio-affecting and body treating compositions
Effervescent or pressurized fluid containing
Organic pressurized fluid
424 45, 424101, 424177, A61K 914, A61K 3514, A61K 3700
Patent
active
044276508
ABSTRACT:
A preparation for accelerated hemostasis and optimized biochemical control of wound closure ("tissue adhesive") consists only of solid, powdery, biologically active constituents and contains 60 to 96% by weight of fibrinogen, which is largely liberated from cryo-insoluble globulin, 0.05 to 5% by weight of a fibrinolysis inhibitor, and 0.1 to 15% by weight of thrombin and/or prothrombin. For use, this enriched plasma derivative may be applied in the form of a dry, powdery mixture immediately and directly onto the wound or in the area of operation, respectively. Further application methods provide atomizing, spraying, or foaming of the powdery mixture by means of a propellant.
REFERENCES:
patent: 2492458 (1949-12-01), Bering
patent: 4298598 (1981-11-01), Schwarz et al.
patent: 4362567 (1982-12-01), Schwarz
McKendrick-Chem. Abst., vol. 76 (1972), p. 17809n.
Bruhn et al.-Chem. Abst., vol. 90 (1979), p. 101085v.
Schwarz et al.-Chem. Abst., vol. 94 (1981), p. 36384h.
Schwarz et al.-Chem. Abst., vol. 94 (1981), p. 36318q.
Hueschen Gordon W.
Rosen Sam
Serapharm Michael Stroetmann
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