Enolamides, pharmaceutical compositions and methods for treating

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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549 54, 549 55, 549 48, C07D33364, A61K 3138

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active

047614242

ABSTRACT:
The present invention relates to novel enolamide type compounds, pharmaceutical compositions, and methods of use thereof, useful in the treatment of diseases in which products of lipoxygenase enzyme activity or the action of leukotrienes contribute to the pathological condition.

REFERENCES:
patent: 3413308 (1968-11-01), Bockstahler
patent: 3591584 (1971-07-01), Lombardino
patent: 3646020 (1972-02-01), Zinnes etal.
patent: 3674876 (1972-07-01), Lombardino
patent: 3803205 (1974-04-01), Shang et al.
patent: 3828073 (1974-08-01), Zinnes et al.
patent: 3862319 (1975-01-01), Lombardino et al.
patent: 3891637 (1975-06-01), Lombardino
patent: 3892740 (1975-07-01), Lombardino
patent: 3900470 (1975-08-01), Rasmussen
patent: 3923801 (1975-12-01), Rasmussen
Lombardino et al., J. of Medicinal Chemistry, vol. 14, No. 12, pp. 1171-1175 (1971).
Zinnes et al., J. of Medicinal Chemistry, vol. 16, No. 1, pp. 44-48 (1973).
Saxena et al., J. of Medicinal Chemistry, vol. 12, p. 1120 (1969).
Goerlitzer, Chemical Abstracts, vol. 83, entry 79112h (1975).
Gayral et al., Chemical Abstracts, vol. 103, entry 66721n.

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