Enlarged-hetero-ring prostacyclin analogs

Details Enlarged-hetero-ring prostacyclin analogs Enlarged-hetero-ring prostacyclin analogs

1977-07-28

1978-10-31

Chan, Nicky

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

424283, 542426, 542439, 542441, 542447, C07D31102, A61K 3135

Patent

active

041234413

ABSTRACT:
Prostaglandin (PG.sub.1) derivatives having (1) a 5-keto feature, for example ##STR1## or (2) a 9-deoxy-5,9-epoxy feature together with a 4-halo or 5-hydroxy feature, for example ##STR2## or a 4,5-didehydro feature, for example in an enol ether of the formula ##STR3## said derivatives having pharmacological activity. Processes for preparing them and the appropriate intermediates are disclosed.

REFERENCES:
pace-Asciak et al., Biochem., 10, 3657 (1971).
Pace-Asciak et al., JACS, 98, 2348 (1976).

Affiliated with

Also associated with

Rating

Enlarged-hetero-ring prostacyclin analogs does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Enlarged-hetero-ring prostacyclin analogs, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Enlarged-hetero-ring prostacyclin analogs will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1834899