Enlarged-hetero-ring prostacyclin analogs

Details Enlarged-hetero-ring prostacyclin analogs Enlarged-hetero-ring prostacyclin analogs

1979-02-15

1980-05-13

Gerstl, Robert

Harness for working animal

542429, 2603452, C07D31194

Patent

active

042029716

ABSTRACT:
Prostaglandin (PG.sub.1) derivatives having (1) a 6-keto feature, together with a 9-deoxy-9-hydroxymethyl feature for example ##STR1## or (2) a 9-deoxy-6,9-epoxymethano feature together with a 5-halo or 6-hydroxy feature, for example ##STR2## or a 5,6-didehydro feature, for example in an enol ether of the formula ##STR3## said derivatives having pharmacological activity. Processes for preparing them and the appropriate intermediates are disclosed.

REFERENCES:
patent: 3435053 (1969-03-01), Beal

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