Enkephalinase inhibitor and GABA precursor loading as...

Drug – bio-affecting and body treating compositions – Inorganic active ingredient containing – Heavy metal or compound thereof

Reexamination Certificate

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C424S602000, C424S641000, C424S675000, C424S678000, C424S681000, C424S682000, C424S683000, C424S686000, C424S687000, C424S688000, C424S692000, C424S693000, C424S696000, C424S697000, C424S722000, C514S249000, C514S251000, C514S345000, C514S419000, C514S474000, C514S494000, C514S553000, C514S556000, C514S561000, C514S563000, C514S567000, C514S578000, C514S809000, C514S811000, C514S812000

Reexamination Certificate

active

10977976

ABSTRACT:
Benzodiazepine withdrawal induced anxiety is treated by administration of an enkephalinase inhibitor, and a gamma-aminobutyric acid (“GABA”) precursor, or an endorphin or enkephalin releaser. These components promote restoration of normal neurotransmitter function and are non-addictive. Use of the enkephalinase inhibitor D-phenylalanine, the GABA precursor glutamine, the serotonin precursor 5-HTP, glycine, and taurine, in combination with coenzymatic functionality of folic acid is preferred for activation of ligand-gated Cl−channel in the central nervous system. Food supplement embodiments provide the human body nutritional supplements to intake certain neurotransmitter precursor substrates, thereby enabling patients of all ages to self-regulate their ability to quell perturbations to equilibrium and simultaneously to adverse effects upon normal physiological and psychological functioning attributable to induced anxiety and panic associated with benzodiazepine withdrawal.

REFERENCES:
patent: 4761429 (1988-08-01), Blum et al.
patent: 5189064 (1993-02-01), Blum et al.
patent: 5922361 (1999-07-01), Bieser et al.
patent: 6159506 (2000-12-01), Bieser et al.
patent: 6955873 (2005-10-01), Blum
patent: 2004/0116351 (2004-06-01), Halevie-Goldman
Medline abstract 93233833 (1993).

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