Enhancing the translational initiation frequency of a gene

Details Enhancing the translational initiation frequency of a gene Enhancing the translational initiation frequency of a gene

1985-07-17

1989-05-02

Wiseman, Thomas G.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Enzymatic production of a protein or polypeptide

435 70, 435 91, 4351723, 4353171, 43525233, 435320, 536 27, 935 6, 935 29, 935 44, 935 73, C12P 2100, C12P 1934, C12N 700, C07H 1512

Patent

active

048267643

ABSTRACT:
The invention concerns the intercistronic DNA sequence of the atp operon of Escherichia coli for the subunit c of the ATP synthase, a DNA structure and an expression vector which are characterized by the said intercistronic DNA sequence, and a process for the production of proteins using the same. The DNA sequence enhances the rate of synthesis of the proteins.

REFERENCES:
Gray et al. (1981), Nucleic Acids Res. 9: 3919-26.
Bruislow et al. (1982), J. Bacteriology 151:1363-7.
Kastelein et al. (1983), Gene 23: 245-54.
McCarthy et al. (1984), Abstract ed EBEC Mtg., Hannover.
Kastelein et al. (1983), Gene, vol. 23, pp. 245-254.

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