Drug – bio-affecting and body treating compositions – Immunoglobulin – antiserum – antibody – or antibody fragment,...
Reexamination Certificate
2007-08-14
2007-08-14
Chan, Christina (Department: 1644)
Drug, bio-affecting and body treating compositions
Immunoglobulin, antiserum, antibody, or antibody fragment,...
C424S133100, C424S155100, C424S094200
Reexamination Certificate
active
10486438
ABSTRACT:
The present invention is directed to a composition and method for enhancing the complement-mediated cytotoxicity of therapeutic antibodies for their target cells (i.e. those cells displaying the target epitope). More particularly the present invention enhances the efficacy of such therapies by providing a supplemental source of complement.
REFERENCES:
Harjunpaa, A et al. Scand. J. Immunol. [2000] 51:634-641.
Gilleece, MH et al. Blood [1993] 82(3):807-812.
Kennedy Adam
Lindorfer Margaret A.
Solga Michael D.
Taylor Ronald P.
Sparks Rodney L.
University of Virginia Patent Foundation
VanderVegt F. Pierre
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