Enhancing bone marrow engraftment using MSCS

Drug – bio-affecting and body treating compositions – Whole live micro-organism – cell – or virus containing – Animal or plant cell

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Details

424422, 424423, 435372, A01N 6300, A61F 200, C12N 500

Patent

active

057335427

ABSTRACT:
Method and preparations for enhancing bone marrow engraftment in an individual by administering (i) a culturally expanded mesenchymal stem cell preparation and (ii) a bone marrow graft. The mesenchymal stem cells are administered in an mount effective to promote engraftment of the bone marrow.

REFERENCES:
patent: 5226914 (1993-07-01), Caplan et al.
patent: 5461034 (1995-10-01), Rodan et al.
Hard. Demonstration of the tumorigenicity of transformed rat kidney cell-lines by intravenous allotransplantation in the neonate. Int. Cancer: 30, 197-202 (1982).

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