Enhancement of xenogeneic tissue

Details Enhancement of xenogeneic tissue Enhancement of xenogeneic tissue

1986-10-14

1989-01-17

Apley, Richard J.

Prosthesis (i.e., artificial body members), parts thereof, or ai

Miscellaneous

623 1, 623 2, 623 11, 623 13, 128DIG8, 128898, 8 9411, 8 941R, A61F 254

Patent

active

047986115

ABSTRACT:
Xenogeneic tissue implants prepared by precrosslinking proteins in xenogeneic tissue using, for example, glutaraldehyde, and thereafter irradiating the crosslinked tissue with high energy radiation, e.g. gamma radiation, to sterilize, reduce the immunogenicity and improve the compliance and physical properties of the tissue are disclosed.

REFERENCES:
patent: 3451394 (1969-06-01), Bechtol et al.
patent: 3453194 (1969-07-01), Bennett et al.
patent: 3823212 (1974-07-01), Chvapil
patent: 3943045 (1976-03-01), Cordrey et al.
patent: 4060081 (1977-11-01), Yannas et al.
patent: 4223984 (1980-09-01), Miyata et al.
patent: 4400833 (1983-08-01), Kurland
Collagen Currents, "Effect of Gamma-Radiation on Leather", Jan. 1966, p. 230.

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