Enhancement of transdermal delivery with ultrasound and chemical

Details Enhancement of transdermal delivery with ultrasound and chemical Enhancement of transdermal delivery with ultrasound and chemical

1993-12-08

1995-08-29

Rosenbaum, C. Fred

Surgery

Means for introducing or removing material from body for...

Material introduced into and removed from body through...

604290, A61M 3700

Patent

active

054456118

ABSTRACT:
A method of enhancing the permeability of the skin or mucosa to a biologically active permeant or drug is described utilizing ultrasound or ultrasound plus a chemical enhancer. If desired the ultrasound may be modulated by means of frequency modulation, amplitude modulation, phase modulation and/or combinations thereof. A frequency modulation from high to low develops a local pressure gradient directed into the body, thus permitting permeant to traverse the skin or mucosa. The enhanced delivery is preferably accomplished using a chemical enhancer, applying ultrasound optionally at a modulated frequency, amplitude, phase, or combinations thereof that further induces a local pressure gradient into the body. The method is also useful as a means for application of a tattoo by noninvasively delivering a pigment through the skin surface.

REFERENCES:
patent: 4372296 (1983-02-01), Fahim
patent: 4646725 (1987-03-01), Moasser
patent: 4767402 (1988-08-01), Kost et al.
patent: 4780212 (1988-10-01), Kost et al.
patent: 4821740 (1989-04-01), Tachibana et al.
patent: 4953565 (1990-09-01), Tachibana et al.
patent: 5007438 (1991-04-01), Tachibana et al.
patent: 5016615 (1991-05-01), Driller
patent: 5171215 (1992-12-01), Flanagan
patent: 5231975 (1993-08-01), Bommannan et al.
patent: 5267985 (1993-12-01), Shimada et al.

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