Drug – bio-affecting and body treating compositions – Whole live micro-organism – cell – or virus containing – Genetically modified micro-organism – cell – or virus
Patent
1988-07-21
1990-11-20
Moskowitz, Margaret
Drug, bio-affecting and body treating compositions
Whole live micro-organism, cell, or virus containing
Genetically modified micro-organism, cell, or virus
424 88, 424534, 514 2, 514 21, 935105, 935107, 4352401, A61K 4505, A61K 3526
Patent
active
049717952
ABSTRACT:
DTH-Effector cells are primed with carbohydrate antigens and used to enhance the cellular immune response. Tumors have been inhibited by DTH-Effector cells primed with epiglycanin and with synthetic T and Tn antigens. Either the DTH-Effector cells, or these tumor-associated carbohydrate antigens directly, may be used for tumor prophylaxis and therapy.
REFERENCES:
patent: 4180627 (1979-12-01), Klesius et al.
patent: 4690915 (1987-09-01), Rosenberg
Ertl, Cell. Immunol., 62, 38-49, (1981).
Benjamin et al., Chapter 15 in Basic and Clincial Immunology, Shtes et al eds, 1984 (5th Edition), Los Altos, Calif.
Lefford, Immunology, 41, 635 (1980).
Chemical Abstracts, 78, 27836z (for Cooper, Scand. J. Immunol, 1(3), 237-45).
Weir et al. (Editors), Handbook of Experimental Immunology, vol. 2, "Cellular Immunology", pp. 75.1-75.7 and 77.1-77.13.
Havelle et al., J. Immunol, 137(5), 1448-54, 1986.
Goldstein et al., J. Exp. Med., 162, p. 1381-1386, (1985).
Greene et al, in Fundamental Immunology, (Paul, Edtr), Raven Press, 1984, pp. 685-696.
Leung et al., J. Exp. Med., 151, 815-26, (1980).
Bianchi et al., Nature, 290, 62-63 (1981).
Klein, ed., Immunology: The Science of Self-Nonself Discrimination 465 (1982).
Myrvik, et al., Fundamentals of Immunology 135-41 (1984).
Moreno, "Carbohydrates as Immunogens and Tolerogens: Antibody versus Cell-Mediated Immune Responses", in Towards Better Carbohydrates Vaccines, Chapter 19 (1987) at pp. 263, 267.
Henningsson Carina
Longenecker B. Michael
Biomira, Inc.
Cooper Iver P.
Kushan Jeff
Moskowitz Margaret
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