Enhancement of porcine somatotropin activity

Details Enhancement of porcine somatotropin activity Enhancement of porcine somatotropin activity

1989-10-27

1993-05-11

Cashion, Jr., Merrell C.

Chemistry: natural resins or derivatives; peptides or proteins;

Peptides of 3 to 100 amino acid residues

8 to 10 amino acid residues in defined sequence

530345, A61K 3702, C07K 100

Patent

active

052101800

ABSTRACT:
This invention is directed to peptide fragments of porcine somatotropin (pST) which are used to generate epitope-specific anti-pST antibodies. When such antibodies are administered with pST to warm-blooded animals, the growth enhancing activity of pST is potentiated.

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Rudinger et al. "Peptide Hormones" (J. A. Parsons-ed.) Jun. 1976 1-6.
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Dictionary-Biochem & Molec Biol. (2nd ed) (Wiley & Sons 1989) at 222.
Abdel-Meguid, S. S. et al., Proc. Natl. Acad. Sci., 84, 6434-6437 (1987).
Groesbeck, M. D., and Parlow, A. F., Endocrinology, 120, 2582-2590 (1987).

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