Chemistry: molecular biology and microbiology – Virus or bacteriophage – except for viral vector or... – Inactivation or attenuation; producing viral subunits
Patent
1997-10-08
1999-02-23
Campell, Bruce R.
Chemistry: molecular biology and microbiology
Virus or bacteriophage, except for viral vector or...
Inactivation or attenuation; producing viral subunits
536 245, 935 34, C12N 706, C07H 2104
Patent
active
058742816
ABSTRACT:
The invention features the use of a purified first targeted oligonucleotide in combination with either 1) a subtargeted oligonucleotide, 2) second targeted oligonucleotide, or 3) a non-targeted phosphorothioate oligonucleotide, to inhibit protein production of a targeted nucleic acid sequence, cell proliferation, and/or the multiplication of a foreign organism. The subtargeted oligonucleotide contains a truncated version of the targeted oligonucleotide.
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Dattagupta Nanibhushan
Kacian Daniel L.
Sridhar C. Nagaraja
Campell Bruce R.
Gen-Probe Incorporated
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