Chemistry: molecular biology and microbiology – Treatment of micro-organisms or enzymes with electrical or... – Modification of viruses
Patent
1994-01-18
1997-06-03
Stone, Jacqueline M.
Chemistry: molecular biology and microbiology
Treatment of micro-organisms or enzymes with electrical or...
Modification of viruses
4353201, 4351721, 424450, 424 862, A61K 4800, C12N 1500
Patent
active
056353804
ABSTRACT:
This invention provides a method of enhancing the delivery of a nucleic acid into a cell, wherein a complex is formed comprising the nucleic acid, a cationic liposome, and a replication-deficient adenovirus, and the complex is administered to the cell to thereby enhance delivery of the nucleic acid into the cell. The method can be used to deliver the nucleic acid into a cell in a subject by administering the above complex into the subject.
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Naftilan Allen J.
Walia Rampyari
Milne Andrew
Stone Jacqueline M.
Vanderbilt University
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