Drug – bio-affecting and body treating compositions – Conjugate or complex of monoclonal or polyclonal antibody,...
Reexamination Certificate
2007-01-02
2007-01-02
Rawlings, Stephen L. (Department: 1643)
Drug, bio-affecting and body treating compositions
Conjugate or complex of monoclonal or polyclonal antibody,...
C530S350000, C530S387100, C530S391700, C424S134100, C424S183100
Reexamination Certificate
active
10446422
ABSTRACT:
A method for enhancing intracellular delivery of effector molecules is provided. The method involves modifying selected antibodies with biotin and streptavidin, conjugating these antibodies with an effector molecule, and delivering the conjugated effector to an intracellular target specifically recognized by the antibody.
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Albelda Steve M.
Muzykantov Vladimir R.
Licata & Tyrrell P.C.
Rawlings Stephen L.
Trustees of the University of Pennsylvania
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