Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Chemical modification or the reaction product thereof – e.g.,...
Patent
1997-01-31
1998-02-03
Ulm, John
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Chemical modification or the reaction product thereof, e.g.,...
435 72, 435 721, 435 695, 435325, 435366, 435371, 424413, 424443, 424486, 530399, A61K 970, A61K 3818, C07K 1708
Patent
active
057145881
ABSTRACT:
A method of producing recombinant transforming growth factor .beta.-induced H3 protein and the use of this protein to accelerate wound healing. H3 promoted adhesion of human dermal fibroblasts to tissue culture plastic. The protein is applied directly to a wound or is used to promote adhesion and spreading of dermal fibroblasts to a solid support such as a nylon mesh which is then applied to the wound. In addition, CHO cells expressing H3 inhibited tumor cell growth.
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LeBaron Richard
Purchio Anthony F.
Advanced Tissue Sciences
Mertz Prema
Ulm John
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