Surgery – Means for introducing or removing material from body for... – Treating material introduced into or removed from body...
Patent
1998-04-09
2000-05-23
Brusca, John S.
Surgery
Means for introducing or removing material from body for...
Treating material introduced into or removed from body...
424450, 514 2, 514 44, 600411, 604 22, A61N 700, A61B 5055, A61K 9127, A61K 4800
Patent
active
060661232
ABSTRACT:
Targeted tissue in vivo is altered using focused energy to specifically control endothelial permeability and interstitial integrity. Image guidance may be used in combination with physical energy deposition to facilitate the targeted delivery of materials. The method of the invention serves as a platform for delivering pharmaceutical agents, nucleic acids, proteins, liposomes, etc. to cells.
REFERENCES:
patent: 4767402 (1988-08-01), Kost et al.
patent: 4948587 (1990-08-01), Kost et al.
patent: 5115805 (1992-05-01), Bommannan et al.
patent: 5247935 (1993-09-01), Cline et al.
patent: 5267985 (1993-12-01), Shimada et al.
patent: 5421816 (1995-06-01), Lipkovker
patent: 5445611 (1995-08-01), Eppstein et al.
patent: 5490840 (1996-02-01), Uzgiris et al.
patent: 5614502 (1997-03-01), Flotte et al.
patent: 5656016 (1997-08-01), Ogden
patent: 5658892 (1997-08-01), Flotte et al.
Bao, Shiping, et al., "Transfection Of A Reporter Plasmid Into Cultured Cells By Sonoporation In Vtro," Ultrasound In Med.& Biol. (1997) vol. 23, No. (6):953-959.
Bednarski, Mark D., et al., "In Vivo Target-Specific Delivery of Macromolecular Agents With MR-Guided Focused Ultrasound.sup.1," Radiology (Jul. 1997) vol. 204, No. (1):263-268.
Tata, Darrell B., et al., "Selective Clinical Ultrasound Signals Mediate Differential Gene Transfer and Expression In Two Human Prostate Cancer Cell Lines: LnCap and PC-3" Biochemical and Biophysical Research Communications (1997) vol. 234:64-67; Article No. RC976578.
Bednarski Mark
Li King
Brusca John S.
Sherwood Pamela
The Board of Trustees of the Leland Stanford Junior University
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