Enhancement of antitumor therapy with hemoglobin-based conjugate

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

530385, 604 20, C70K 14805, A61K 3842

Patent

active

054788064

ABSTRACT:
The use of hemoglobin-polymer conjugates to enhance antitumor therapy in mammals is disclosed. The methods include administering an effective amount of an antitumor therapy such as radiation in combination with hemoglobin conjugated to a substantially non-antigenic polymer.

REFERENCES:
patent: 3966902 (1976-06-01), Chromecek
patent: 4179337 (1979-12-01), Davis et al.
patent: 4861876 (1989-08-01), Kessel
patent: 5122614 (1992-06-01), Zalipsky
patent: 5173426 (1992-12-01), Fischer et al.
patent: 5234903 (1993-08-01), Nho et al.
patent: 5239061 (1993-08-01), Fronticelli et al.
patent: 5264555 (1993-11-01), Shorr et al.
patent: 5295944 (1994-03-01), Teicher et al.
patent: 5296465 (1994-03-01), Rausch et al.
patent: 5296466 (1994-03-01), Kilbourn et al.
patent: 5312808 (1994-05-01), Shorr et al.
Teicher et al., Art. Cells, Blood Subs., and Immob. Biotech. 22(3) 827-833 (1994).
Teicher et al., Biomat., Art. Cells & Immob. Biotech. 20(2-4), 657-660 (1992).
Teicher, Biomat., Art. Cells & Immob. Biotech., 20(2-4), Var. 875-910 (1992).
Teicher et al, Biomat., Art. Cells & Immob. Biotech., 20(2-4), 657-660 (1992).
Nho et al, "Increased Oxy. Ten. in Sol. Tum. following PEG-Hb trans.", Blood Substitutes & Related Prod., IBC, Philadelphia, (Sep. 21-22, 1993.
Hirst et al Br. J. Cancer, 55, 487-491 (1987).
Siemen et al, Int. J. Radiation Oncol. Biol. Phys., 16, 1169-1172 (1989)
Teicher et al, J. Cancer Res. Clin. Oncol., 118, 123-128 (1992).
Wu et al, Cancer Res., 53, 3765-3770 (Aug. 15, 1993).
Winslow, "Hemoglobin Based Blood Substitutes", Blood Substitutes & Related Products, IBC, Philadelphia (Sep. 21-22, 1993).
Coleman, ASTRO Refresher Course #409 "Hypoxic Cell Sensitizers" (Oct. 18, 1990).
Teicher et al, Biomat., Art. Cells, Art. Org., 16(1-3) 533-546 (1988).
Rockwell, Biomat., Art. Cells, Art. Org., 16(1-3), 519-531 (1988).

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Enhancement of antitumor therapy with hemoglobin-based conjugate does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Enhancement of antitumor therapy with hemoglobin-based conjugate, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Enhancement of antitumor therapy with hemoglobin-based conjugate will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-1369217

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.