Enhancement of abnormal tissue uptake of antibodies, tumor-speci

Drug – bio-affecting and body treating compositions – Radionuclide or intended radionuclide containing; adjuvant... – Attached to antibody or antibody fragment or immunoglobulin;...

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424 9, 424 4, 4241821, A61K 4902, A61K 4900, A61K 39395

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active

053993381

ABSTRACT:
Biomodulators, in conjunction with antibodies, tumor-specific agents or conjugates thereof, optionally linked to imaging-active moieties, can be administered to a host to enhance images thereof, e.g., NMR-, X-ray- or radioimages, preferably by increasing aberrant tissue signal intensity.

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Mann et al., "Cell Surface Oligosaccharide Modulation during Differentiation: IV. Normal and Transformed Cell Growth Control," Mechanisms of Ageing and Development, 44 (1988), pp. 17-33.

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