Enhanced sequencing by hybridization using pools of probes

Details Enhanced sequencing by hybridization using pools of probes Enhanced sequencing by hybridization using pools of probes

2005-03-08

2005-03-08

Moran, Marjorie (Department: 1631)

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving nucleic acid

C435S091100, C435S091520, C536S023100, C536S024320, C536S025300

Reexamination Certificate

active

06864052

ABSTRACT:
The invention provides methods for sequencing by hybridization (SBH) using pools of probes that allow greater efficiency in conducting SBH by reducing the number of separate measurements of hybridization signals required to identify each particular nucleotide in a target nucleic acid sequence. The invention also provides pools and sets of pools of probes, as well as methods of generating pools of probes.

REFERENCES:
patent: 5002867 (1991-03-01), Macevicz
patent: 5202231 (1993-04-01), Drmanac et al.
patent: 6355419 (2002-03-01), Alfenito
patent: 6537755 (2003-03-01), Drmanac
patent: WO 9509248 (1995-04-01), None
patent: WO 9511995 (1995-04-01), None
patent: WO 9617957 (1996-06-01), None
patent: WO 9831836 (1998-07-01), None
International Search Report from PCT/US00/00458.

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