Enhanced production of taxol and taxanes by cell cultures of tax

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing heterocyclic carbon compound having only o – n – s,...

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435 41, 435127, 4352404, 43524046, 43524048, 549510, 549511, C12P 1702, C12P 1500

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054078164

ABSTRACT:
This invention is directed to methods for the enhanced production and recovery of taxol and taxanes by cell cultures of Taxus species.

REFERENCES:
patent: 5019504 (1991-05-01), Christen et al.
Chemical Abstract 112:3779c vol. 112, No. 1, 01 Jan. 1990, Xu et al., "Determination of taxol in the extract of Taxus chinensis by reversed phase HPLC" abstract of Yaoxue Xuebao 1989, 24(7) 552-5.
Chemical Abstract 1162:124148n, vol. 116, No. 13, 30 Mar. 1992 Xu et al., "Determination of taxol in Taxus chinensis by HPLC method" abstract of Yaoxue Xuebao 1991, 26(7) 537-540.
Chem Abs 116:55524t vol. 16 No. 7 (Feb. 17, 1992) Jia et al "Chin Sci Bull" (1991) 36(14) 1174-7.
Chem Abs 117:8234j vol. 117 No. 1 (Jul. 6, 1992) Jia et al. "Chin Sci Bull" 1991 36 (23) 1967-9.
Chem Abs 113:208344z vol. 113 (Dec. 3, 1990) Zhang et al. "Plant Med" 1990 (56)3, 293-4.
Chem Abs 131964h vol. 115 (Sep. 30, 1991) Zhang et al. "Phytochem" (1991) 30(7) 2345-8.

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