Enhanced production of blood components, blood cells and...

Drug – bio-affecting and body treating compositions – Designated organic nonactive ingredient containing other... – Carboxylic acid or salt thereof

Reexamination Certificate

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C514S785000

Reexamination Certificate

active

10280501

ABSTRACT:
The blood collection, processing and transfer by separation of discrete components containing additional citrate (at least about trisodium citrate 2% w/v) in one or other of collection or processing bag provides for enhanced yield and purity of cryoprecipitate. Inhibiting the activation or denaturation of blood components including blood cells and plasma proteins and with the removal of the activated and denatured components thereby improving safety and efficacy of end products, which include fibrin glue, is achieved. In addition, the process allows “cryo” precipitate to be prepared at temperatures above freezing and without freezing the plasma.

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