Enhanced oral and transcompartmental delivery of therapeutic...

Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Tablets – lozenges – or pills

Reexamination Certificate

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Details

C530S327000, C514S002600, C424S001690

Reexamination Certificate

active

07740882

ABSTRACT:
The invention is directed to pharmaceutical compositions and methods for delivery of a therapeutic or diagnostic agent from one bodily compartment to one or more other bodily compartment by administering one of the following conjugates: a polymer having multiple functional groups at least one of which is covalently bound to a therapeutic or diagnostic agent, and at least one cell uptake promoter covalently bound to the therapeutic or diagnostic agent; or a polymer and at least one cell uptake promoter bound thereto; the polymer further comprising multiple functional groups at least one of which is covalently bound a therapeutic or diagnostic agent.

REFERENCES:
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patent: 6258774 (2001-07-01), Stein et al.
patent: WO 99/47173 (1999-09-01), None
patent: WO9947173 (1999-09-01), None
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Goodwin, J.T. et al. Journal of Peptide Res vol. 53: pp. 355-369 (1999).

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