Enhanced immunogenicity using leukotoxin chimeras

Details Enhanced immunogenicity using leukotoxin chimeras Enhanced immunogenicity using leukotoxin chimeras

1992-10-14

1995-06-06

Sidberry, Hazel F.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

4241841, 4241901, 4241921, 4242341, 530350, 530825, 435 693, 4351721, 4351723, 435 691, 536 234, 536 237, A61K 39102, C12N 1531

Patent

active

054221102

ABSTRACT:
New immunological carrier systems, DNA encoding the same, and the use of these systems, are disclosed. The carrier systems include chimeric proteins which comprise a leukotoxin polypeptide fused to a selected antigen. The leukotoxin functions to increase the immunogenicity of the antigen fused thereto.

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