Enhanced immunogenicity using leukotoxin chimeras

Details Enhanced immunogenicity using leukotoxin chimeras Enhanced immunogenicity using leukotoxin chimeras

1995-05-31

1998-01-13

Housel, James C.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

536 237, 435 691, 435 693, 435 697, 4351721, 4351723, 4242351, C07H 204, C07H 202, C12P 2106, A61K 3902

Patent

active

057081557

ABSTRACT:
New immunological carrier systems, DNA encoding the same, and the use of these systems, are disclosed. The carrier systems include chimeric proteins which comprise a leukotoxin polypeptide fused to a selected antigen. The leukotoxin functions to increase the immunogenicity of the antigen fused thereto.

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