Chemistry: molecular biology and microbiology – Virus or bacteriophage – except for viral vector or... – Recovery or purification
Reexamination Certificate
2005-01-11
2005-01-11
Housel, James (Department: 1648)
Chemistry: molecular biology and microbiology
Virus or bacteriophage, except for viral vector or...
Recovery or purification
C435S235100, C435S236000, C424S204100, C424S218100
Reexamination Certificate
active
06841374
ABSTRACT:
The present invention provides a novel inactivated virus particle and a reinforced immunogen which have a reinforced titer about twice to about 10 times that of a conventional vaccine, as well as a method for producing the same. The inactivated virus particle is produced by inactivating and then purifying a culture by physical means. The inactivated virus particle of the present invention is useful in a diagnostic agent for infectious disease caused by a group of Japanese encephalitis virus.
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Huiying, S., et al., “Large-Scale Purification of Inactivated Japanese Encephalitis Vaccine from Vero Cells by Zonal Centrifugation” Virologica Sinica 13(3):213 (1998) abstract only.
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International Search Report from Application No. EP 99 92 3858, (2001).
Imagawa Tadashi
Ishibashi Masahide
Ishikawa Toyokazu
Onishi Toshiyuki
Yoshii Hironori
Chen Stacy B.
Housel James
Mahoney Jacqueline F.
Mohr Judy M.
Perkins Coie LLP
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