Enhanced gene expression in response to lactation signals

Details Enhanced gene expression in response to lactation signals Enhanced gene expression in response to lactation signals

1993-06-02

1994-06-14

Chambers, Jasemine C.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Recombinant dna technique included in method of making a...

4351723, 4353201, 536 241, 935 33, 935 34, 935 36, C12N 1500, C07H 2100

Patent

active

053209524

ABSTRACT:
An expression method for enhanced recombinant production of a desired protein due to the presence of lactation-signals is provided which comprises cells transformed with a DNA sequence having the desired protein coding sequence under the control of a bovine prolactin promoter and a bovine prolactin distal enhancer sequence. A preferred embodiment uses growth hormone sequences as the desired protein coding sequences. In this embodiment, feed-efficiency of milk-producing animals is improved.

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