Chemical apparatus and process disinfecting – deodorizing – preser – Analyzer – structured indicator – or manipulative laboratory... – Means for analyzing liquid or solid sample
Patent
1994-06-23
1996-01-16
Housel, James C.
Chemical apparatus and process disinfecting, deodorizing, preser
Analyzer, structured indicator, or manipulative laboratory...
Means for analyzing liquid or solid sample
422 8205, 204299R, 2041801, G01N 2131, G01N 2101, G01N 27447
Patent
active
054845718
ABSTRACT:
A simple device for collecting a greater amount of fluorescent emission from a minute sample in a capillary column. An axially symmetrical paraboloid reflector is implemented to collect fluorescent emission from the capillary column. The reflector also serves as a simple bracket for positioning and aligning the capillary column. Fluorescent emission is collimated by the paraboloid reflector which allows more effective use of band pass filters in blocking scattered radiation from detection. The scattered and transmitted radiation can be used to facilitate alignment of the capillary with respect to the detection optics. The paraboloid reflector also facilitates the implementation of simultaneous multiple-channel detection.
REFERENCES:
patent: 3795450 (1974-03-01), Munk
patent: 3985441 (1976-10-01), Schoeffel et al.
patent: 4088407 (1978-05-01), Schoeffel
patent: 4172227 (1979-10-01), Tyrer et al.
patent: 4199686 (1980-04-01), Brunsting et al.
patent: 4273443 (1981-06-01), Hogg
patent: 4367040 (1983-01-01), Goto
patent: 4565448 (1986-01-01), Abbott et al.
patent: 4657397 (1987-04-01), Oehler et al.
patent: 4675300 (1987-06-01), Zare et al.
patent: 4786171 (1988-11-01), LeFebre et al.
patent: 4801552 (1989-01-01), Hoff
patent: 4838688 (1989-06-01), Rhoads
patent: 4854700 (1989-08-01), Cutie et al.
patent: 4927265 (1990-05-01), Brownlee
patent: 4929561 (1990-05-01), Hirschfeld
patent: 4997275 (1991-03-01), Gaucher et al.
patent: 5062942 (1991-11-01), Kambara et al.
patent: 5108179 (1992-04-01), Myers
patent: 5292483 (1994-03-01), Kaye et al.
Pentoney, S. L. Jr., Huang, X., Burgi, D., & Zare, R. N.; "On-Line Connector For Microcolumns: Application to the On-Column o-Phthaldialdehyde Derivatization of Amino Acids Separated by Capillary Zone Electrophoresis"; Anal. Chem. 1988, 60, pp. 2625-2629.
Folestad, S., Johnson, L. & Josefsson, B.; "Laser Induced Fluorescence Detection for Conventional and Microcolumn Liquid Chromatography"; Anal. Chem. 1982, 54, pp. 925-929.
Folestad, S., Galle B., Josefsson, B.; "Small-Bore LC/Laser Fluorescence"; Journal of Chromatographic Science, vol. 23, Jun. 1985.
J. V. Sweedler, et al; "Fluorescence Detection in Capillary Zone Electrophoresis Using a Charge-Coupled Device with Time-Delayed Integration"; Analytical Chemistry, vol. 63, No. 5, Mar. 1991, pp. 496-502.
Bornhop, D. et al; "Simultaneous Laser-Based Refractive Index and Absorbance Determinations Within Micrometer Diameter Capillary Tubes"; Anal. Chem. (1987) pp. 1632-1637.
Herzenberg, et al; "Fluorescence-activated Cell Sorting"; Scientific American (1976), vol. 234, N3, pp. 108-117.
Pentoney, et al; "On-Column Radioisotope Detection"; developed from ACS Symposium Series No. 434, pp. 60-89.
Kaye Wilbur
Pentoney, Jr. Stephen L.
Beckman Instruments Inc.
Harder Paul R.
Housel James C.
May William H.
McGlashen Michael L.
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