Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Web – sheet or filament bases; compositions of bandages; or...
Patent
1997-08-12
1999-12-21
Dees, Jose' G.
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Web, sheet or filament bases; compositions of bandages; or...
424400, 424448, 424449, 514788, 514772, 514318, A61K 970
Patent
active
060045779
ABSTRACT:
Improved electrotransport of therapeutic agents which include agent cations and polybasic anionic counterions. Improved electrotransport is obtained by treating the therapeutic agent with a multivalent metal compound of the formula MX where M is a metallic cation having a valency of at least +2 and is reactive with the polybasic anionic counter ion and X is a pH-increasing anion. Reduction in species which compete with the therapeutic agent for electrotranport is obtained.
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Dees Jos,e G.
Shelborne Kathryne E.
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