Enhanced activation of NK cells using an NK cell activator and a

Details Enhanced activation of NK cells using an NK cell activator and a Enhanced activation of NK cells using an NK cell activator and a

1997-09-17

2000-05-16

Celsa, Bennett

Drug, bio-affecting and body treating compositions

Lymphokine

Interleukin

424 851, 424 854, 424 855, 424 856, 424 857, 530351, 514 21, 514400, 514885, 514889, A61K 4500, A61K 3821, C07K 100, C07K 1400

Patent

active

060633735

ABSTRACT:
An improved method for the prevention of the inactivation of natural killer (NK) cells and the enhanced activation of NK cells in the presence of monocytes using a combination of a natural killer cell activator and a compound effective to inhibit the production or release of intracellular hydrogen peroxide, or a hydrogen peroxide scavenger, is disclosed. The method is useful, for example, in the treatment of solid tumors, metastases and viral infection.

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