Engraftment of immune-deficient mice with human cells

Details Engraftment of immune-deficient mice with human cells Engraftment of immune-deficient mice with human cells

1994-10-17

1999-11-30

Campbell, Bruce R.

Multicellular living organisms and unmodified parts thereof and

Nonhuman animal

424 931, 424529, 424573, 424577, C12N 1500, A61K 3500

Patent

active

059946172

ABSTRACT:
A process for transplanting into an immunodeficient mouse, which is deficient in T-cells and B-cells, human cells to form a chimeric mouse is provided. The transplanted human cells proliferate and thereby permit in vivo study of the human cells. The human cells are isolated from a human tissue source. The process comprises:

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