Energy transfer dyes

Organic compounds -- part of the class 532-570 series – Organic compounds – Chalcogen in the nitrogen containing substituent

Reexamination Certificate

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Details

C435S006120, C549S223000, C549S224000, C549S227000, C536S026600

Reexamination Certificate

active

06967250

ABSTRACT:
Energy transfer dyes, their preparation, and their use as labels in biological systems is disclosed. The dyes are preferably in the form of cassettes which enable their attachment to a variety of biological materials. The dyes and the reagents that can be made from them offer a wide variety of fluorescent labels with large Stokes' shifts enabling their use in a variety of fluorescence applications over a wide range of the visible spectrum.

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Lee (Nucleic Acids Res 20, 2471, 1992).
Auerbach, Joseph (Journal of Organic Chemistry 41(4), 725-6, 1976).
Basha, Anwer (Tetrahedron Letters (17), 1465-8, 1977).
Southwick et al., “Cyanine Dye Labeling Reagents—Carboxymethylindocyanine Succinimidyl Esters,”Cytometryv. 11, pp. 418-430 (1990).
Mjumadar et al., “Cyanine Dye Labeling Reagents: Sulfoindocyanine Succinimidyl Esters,”Bioconjugate Chemistry, v.4, pp. 105-111 (1993).
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