Endotoxin-specific assay

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Carbohydrate doai

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53612312, 435 4, 435 34, 436 63, 436 74, A61K 31715, C12Q 100, C12Q 104

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059983892

ABSTRACT:
.beta.-1,4-glucans, particularly cellobiose, can be used to inhibit the glucan-specific enzymatic pathway in an amebocyte lysate. So inhibited, the amebocyte lysate can then be used to specifically detect endotoxin in a test sample. .beta.-1,4-glucan inhibitors can be used in a variety of amebocyte lysate assays, including kinetic-chromogenic, end-point chromogenic, turbidimetric, gel-clot, and ELISA assays.

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