Endotoxin binding and neutralizing protein and uses thereof

Details Endotoxin binding and neutralizing protein and uses thereof Endotoxin binding and neutralizing protein and uses thereof

1995-06-07

1997-05-06

Wax, Robert A.

Chemistry: natural resins or derivatives; peptides or proteins;

Proteins, i.e., more than 100 amino acid residues

C07K 1400

Patent

active

056272669

ABSTRACT:
Endotoxin binding
eutralizing proteins capable of binding endotoxin in vivo, thereby neutralizing the toxic effect or bioactivity of endotoxin which are isolated from a horseshoe crab such as Limulus polyphemus, pharmaceutical compositions and pharmaceutical uses of the proteins, a method of purifying the proteins and an assay for endotoxin based on the proteins, are disclosed.

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