Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1996-07-26
1997-12-23
Bond, Robert T.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
546 80, 546 89, 546 92, C07D491048, C07D51304, A61K 31395
Patent
active
057008078
ABSTRACT:
Novel compounds of the formula ##STR1## in which --Y--Z--, R.sup.1 R.sup.2, R.sup.3, R.sup.4, R.sup.5 and X have the meaning indicated and their salts show endothelin receptor-antagonistic properties.
REFERENCES:
patent: 4985422 (1991-01-01), North et al.
patent: 5292740 (1994-03-01), Burri et al.
Rose, Ulrich, "5-Oxo-1,4-dihydroindenopyridines: Calcium Modulators . . . " J. Heterocyclic Chem., 27, 1990, pp. 237-242.
Christadler Maria
Dorsch Dieter
Mederski Werner
Osswald Mathias
Schmitges Claus J.
Bond Robert T.
Merck Patent Gesellschaft mit beschrankter Haftung
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