Endotheliase-2 ligands

Details Endotheliase-2 ligands Endotheliase-2 ligands

2007-09-25

2007-09-25

Helms, Larry R. (Department: 1643)

Drug, bio-affecting and body treating compositions

Immunoglobulin, antiserum, antibody, or antibody fragment,...

Monoclonal antibody or fragment thereof

C435S338000, C435S069100, C435S320100, C530S388260, C536S023530

Reexamination Certificate

active

10916758

ABSTRACT:
Proteins that bind to ET2, such as immunoglobulins that inhibit ET2 with high affinity and selectivity, are provided. The ET2 binding proteins can be used to treat a variety of disorders, including angiogenesis-associated disorders.

REFERENCES:
patent: 5530101 (1996-06-01), Queen et al.
patent: 6734006 (2004-05-01), Xiao et al.
patent: 2002/0068320 (2002-06-01), Shi et al.
patent: 2004/0001801 (2004-01-01), Madison et al.
patent: 2004/0048335 (2004-03-01), Baker et al.
patent: 2004/0067505 (2004-04-01), Alvarez et al.
patent: 2004/0073015 (2004-04-01), Baker et al.
patent: 1262193 (2002-12-01), None
patent: WO 00/78961 (2000-02-01), None
patent: WO 00/12708 (2000-03-01), None
patent: WO 00/37504 (2000-06-01), None
patent: WO 00/50061 (2000-08-01), None
patent: WO 00/68247 (2000-11-01), None
patent: WO 01/36604 (2001-05-01), None
patent: WO 01/36645 (2001-05-01), None
patent: WO 01/68848 (2001-09-01), None
patent: WO 01/96538 (2001-12-01), None
patent: WO 02/086085 (2002-10-01), None
patent: WO 02/070648 (2002-12-01), None
Burgess et al, Journal of Cell Biology vol. 111 Nov. 1990 2129-2138.
Lazar et al Molecular and Cellular Biology Mar. 1988 vol. 8 No. 3 1247-1252.
Schwartz et al, Proc Natl Acad Sci USA vol. 84:6408-6411 (1987).
Lin et al Biochemistry USA vol. 14:1559-1563 (1975).
Rudikoff et al. (Proc. Natl. Acad. Sci USA 1982 79:1979).
Libby et al. (Circulation Res. 89:195-197 (2001).
International Search Report.
U.S. Appl. No. 60/089,125.
Brown et al., Exs., vol. 79, pp. 233-269 (1997).
Carmeliet and Jain, Nature, vol. 407, pp. 249-257 (2000).
Folkman et al., Science, vol. 235, pp. 442-447 91987).
Genbank entry BAB55376 submitted May 10, 2001.
Genbank entry BAB39741 submitted Sep. 12, 2000.
Genbank entry CAC41266 submitted Jun. 12, 2001.
Genbank entry AX149577 submitted Jun. 12, 2001.
Hanahan and Folkman, Cell, vol. 86, pp. 353-364 (1986).
Jankun et al., Cancer Research, vol. 57, pp. 559-563 (1997).
Lang and Schuller, Br. J. Cancer, vol. 84, pp. 234-243 (2001).
Markland et al., Biochemistry, vol. 35, pp. 8045-8057 (1996).
Min et al., Cancer Research, vol. 56, pp. 2428-2433 (1996).
Moses et al., Science, vol. 248, pp. 1408-1410 (1990).
Sigrist et al., Brief Bioinform, vol. 3, pp. 265-274 (2002).
International Search Report dated Aug. 20, 2005.
International Preliminary Search Report dated Sep. 29, 2005.

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