Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Patent
1993-03-03
1998-05-26
Hutzell, Paula K.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
435 792, 43524027, 435 7021, 435188, 435 721, 436548, 5303871, 5303881, 5303911, 5303913, G01N 33567
Patent
active
057563012
ABSTRACT:
The present invention provides two monoclonal antibodies capable of binding to taxol and taxol-like substances which are produced by hybridomas designated 69E4A8E, having ATCC Accession No. HB11281 and 29B7B3C, having ATCC Accession No. HB11280. The present invention also provides a method for detecting the presence of taxol or a taxol-like substance in a sample, a method for screening for a ligand in a subject which is not being treated with taxol, an endogenous taxol-like substance in human serum detected by this screening method, a method of quantitatively determining the amount of taxol or taxol-like substance in a biological fluid sample and a kit for assaying for taxol or a taxol-like substance in a sample.
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Chen Bi-Xing
Erlanger Bernard F.
Leu Jyh-Gang
Bakalyar Heather A.
Hutzell Paula K.
The Trustees of Columbia University in the City of New York
White John P.
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