Endogeneous nucleic acid fragment associated with an...

Details Endogeneous nucleic acid fragment associated with an... Endogeneous nucleic acid fragment associated with an...

2003-08-04

2009-12-15

Kapushoc, Stephen (Department: 1634)

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

C536S024300, C536S023500, C435S006120

Reexamination Certificate

active

07632931

ABSTRACT:
The invention concerns an endogenic nucleic fragment, such as an isolated retrovirus, integrated in the human DNA genome, the fragment being characterized in that it comprises, or consists of, at least part of the gag gene of an endogenetic retrovirus associated with an autoimmune disease or pregnancy failure or pregnancy pathologies, said part at least coding, directly and indirectly, for an expression product, or the complement of the fragment.

REFERENCES:
patent: 5474796 (1995-12-01), Brennan
patent: 0 731 168 (1996-09-01), None
patent: 2 737 500 (1997-02-01), None
patent: 2 765 588 (1999-01-01), None
patent: WO 93/07259 (1993-04-01), None
patent: WO 93/20188 (1993-10-01), None
patent: WO 94/28138 (1994-12-01), None
patent: WO 95/21256 (1995-08-01), None
patent: WO 98/23755 (1998-06-01), None
patent: WO 9823755 (1998-06-01), None
patent: WO 99/02696 (1999-01-01), None
Blast 2 Sequence 'Align Seq ID 1:2, pp. 1-3.
Mayer J et al ‘Human endogenous retrovirus K homologous sequences and their coding capacity in Old World primates.’ J Virol. Mar. 1998;72(3):1870-5.
Chan E ‘ Integrating Transcriptomics and Proteomics’. Apr. 2006, Genetics and Proteomics, available online at www.genpromag.com, pp. 1-5.
Newton MA ‘On differential variability of expression ratios: improving statistical inference about gene expression changes from microarray data’. J Comput Biol. 2001;8(1):37-52.
Lucentini J ‘Gene Association Studies Typically Wrong’ The Scientist (Dec. 20, 2004) p. 20.
Thisted RA ‘What is a P-value?’ (1998) available online at http://www.stat.uchicago.edu?˜thisted, pp. 1-6.
P K Chanda and A K Banerjee ‘Identification of promoter-proximal oligonucleotides and a unique dinucleotide, pppGpC, from in vitro transcription products of vesicular stomatitis virus.’ J Virol. Jul. 1981; 39(1): 93-103.
Perron H et al ‘Molecular identification of a novel retrovirus repeatedly isolated from patients with multiple sclerosis. The Collaborative Research Group on Multiple Sclerosis.’ Proc Natl Acad Sci U S A. Jul. 8, 1997;94(14):7583-8.
Seifarth W et al ‘Proviral structure, chromosomal location, and expression of HERV-K-T47D, a novel human endogenous retrovirus derived from T47D particles.’ J Virol. Oct. 1998;72(10):8384-91.
Zsigmond E. et al. Journal of Lipid Research, vol. 36, 1995, p. 1453-1462.
Drwinga H.L. et al. NIGMS human/rodent somatic cell hybrid mapping panels 1 and 2. Genomics. May 1993;16(2):311-4. Absttract Only Provided.
Sambrook, J., et al., Molecular Cloning, A Laboratory Manual, Cold Spring Harbor Laboratory Press, 1989.
Drwinga, H.L., et al., “NIGMS Human/Rodent Somatic Cell Hybrid Mapping Panels 1 and 2,” Genomics, vol. 16, pp. 311-314, 1993.
Laemmli, U.K., “Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4,” Nature, vol. 227, pp. 680-685, Aug. 15, 1970.
Towbin, H., et al., “Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: Procedure and some applications,” Proc. Natl. Acad. Sci. USA, vol. 76, No. 9, pp. 4350-4354, Sep. 1979.

Affiliated with

Also associated with

Rating

Endogeneous nucleic acid fragment associated with an... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Endogeneous nucleic acid fragment associated with an..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Endogeneous nucleic acid fragment associated with an... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-4119859