Endocrine cell stimulation by neurotrophic agents

Details Endocrine cell stimulation by neurotrophic agents Endocrine cell stimulation by neurotrophic agents

1991-05-15

1993-07-20

Wityshyn, Michael G.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

514 8, 514 21, A61K 3702, A61K 3512

Patent

active

052293653

ABSTRACT:
The disclosure relates to the stimulation of an endocrine cell, in particular a pancreatic cell or its precursor, to grow and divide upon exposure to a neurotrophic agent such as nerve growth factor, laminin or both.

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Yada, et al, Journal of Biological Chemistry 264:2455-2462 (1989).
Zawalich, et al., Endocrinology 125:2400-2406 (1989).
Santos and Rojas, FEBS Letters 249:411-417 (1989).
Edwards et al Cell, vol. 58, pp. 161-170 Jul. 14, 1989.
Levi-Montalcini, Science 237:1154-1162 (1987).

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