Encoded combinatorial chemical libraries

Details Encoded combinatorial chemical libraries Encoded combinatorial chemical libraries

1992-03-30

1996-11-12

Jones, W. Gary

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving nucleic acid

435 794, C12Q 168, G01N 3353

Patent

active

055739059

ABSTRACT:
The present invention describes an encoded combinatorial chemical library comprised of a plurality of bifunctional molecules having both a chemical polymer and an identifier oligonucleotide sequence that defines the structure of the chemical polymer. Also described are the bifunctional molecules of the library, and methods of using the library to identify chemical structures within the library that bind to biologically active molecules in preselected binding interactions.

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