Encapsulation process

Details Encapsulation process Encapsulation process

1990-06-20

1993-07-13

Yarbrough, Amelia Burgess

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Liposomes

424417, 435 6, A61K 3722

Patent

active

052271706

ABSTRACT:
A process for the encapsulation of oligonucleotides in liposomes includes the suspending of liposomes containing a divalent cation in a solution containing an oligonucleotide and having an osmolarity of a less than that of the internal aqueous phase.

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Paul G. Lurquin, Entrapment of Genetic Material into Liposomes and Delivery to Cells in Liposome Technology vol. II, Chapter 13. pp. 188-193, CRC Press, Boca Raton, Fla. (1984).
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